Total Adverse Childhood Experiences and Preterm Birth: A Systematic Review

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dc.contributor.authorSulaiman, Salima
dc.contributor.authorPremji, Shahirose
dc.contributor.authorTavangar, Farideh
dc.contributor.authorYim, Ilona
dc.contributor.authorLebold, Margaret
dc.date.accessioned2021-06-04T13:56:37Z
dc.date.available2021-06-04T13:56:37Z
dc.date.issued2021-05-26
dc.description.abstractIntroduction Total adverse childhood experiences (ACEs) are gaining prominence as a risk factor for preterm birth (PTB). The emerging literature examining this relationship reports inconsistent findings. The purpose of this systematic review was to summarize the available evidence exploring whether total ACEs predict PTB. Methods A total of 386 studies were returned from searches on PubMed, PsycINFO, and Cumulative Index to Nursing and Allied Health Literature (CINAHL). Nine studies were selected for final analysis and synthesis based on reporting of total ACEs and preterm birth gestational weeks or standard definition of birth before 37 weeks’ gestational age. A systematic review rather than meta-analysis was selected to present the findings given the clinical and methodological (e.g., sample studied, measurement tools) heterogeneity of the retrieved studies and pregnancy outcomes measured. Results The nine studies report on birth outcomes for 6,087 women from a range of sociodemographic and ethnic backgrounds. Despite a wide range of study designs, measurement tools, and timings of ACEs exposure across studies, seven of the nine included studies showed significant relationships between ACEs and PTB. Conclusion Systematic review of the literature suggests that total ACEs are associated with PTB and provides an overview on the known associations. However, to date only nine studies have assessed this link, and more studies are needed, to explore the associations between ACEs and PTB using appropriate and valid instruments and doing so among more diverse populations. Future research should also explore possible biological mechanisms (allostatic load), and moderating and mediating variables.en_US
dc.identifier.citationSulaiman, S., Premji, S.S., Tavangar, F. et al. Total Adverse Childhood Experiences and Preterm Birth: A Systematic Review. Matern Child Health J (2021). https://doi.org/10.1007/s10995-021-03176-6en_US
dc.identifier.issn1573-6628
dc.identifier.urihttps://doi.org/10.1007/s10995-021-03176-6en_US
dc.identifier.urihttp://hdl.handle.net/10315/38328
dc.language.isoenen_US
dc.publisherMaternal and Child Health Journalen_US
dc.rightsThis is a post-peer-review, pre-copyedit version of an article published in Maternal and Child Health Journal. The final authenticated version is available online at: https://link.springer.com/article/10.1007/s10995-021-03176-6. More information on Springer Nature terms of reuse for archived author accepted manuscripts (AAMs) of subscription articles can be found at https://www.springer.com/gp/open-access/publication-policies/aam-terms-of-use.en_US
dc.rights.articlehttps://link.springer.com/article/10.1007/s10995-021-03176-6en_US
dc.rights.journalhttps://www.springer.com/journal/10995en_US
dc.rights.publisherhttps://www.springer.com/usen_US
dc.subjectAdverse childhood experiencesen_US
dc.subjectPreterm birthen_US
dc.subjectChildhood maltreatmenten_US
dc.subjectChildhood household dysfunctionen_US
dc.titleTotal Adverse Childhood Experiences and Preterm Birth: A Systematic Reviewen_US
dc.typeArticleen_US

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