Development of Exposure Biomarkers for the Honey Bee (Apis mellifera): Neonicotinoids Versus Traditional Pesticides

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dc.contributor.advisorZayed, Amro
dc.contributor.authorJamieson, Aidan Robert
dc.date.accessioned2023-03-28T21:22:26Z
dc.date.available2023-03-28T21:22:26Z
dc.date.copyright2022-12-21
dc.date.issued2023-03-28
dc.date.updated2023-03-28T21:22:26Z
dc.degree.disciplineBiology
dc.degree.levelMaster's
dc.degree.nameMSc - Master of Science
dc.description.abstractPollination is a vital ecosystem service crucial for reproduction of flowering plants, including agricultural crops. The western honey bee, Apis mellifera, is the most used managed pollinator worldwide. The use and overuse of agrochemicals is hypothesized to have played a role in increasing rates of colony mortality in Canada and globally. The identity of stressors affecting a colony is difficult to discern; information critical for diagnosing and managing honey bee colony health. Here, I explored the potential of using gene expression profiles as diagnostic biomarkers for exposure to various agrochemicals in honey bees. I found genes differentially expressed unique to each stressor, which could be putative biomarkers for specific agrochemical exposure. I found genes common between pesticides, which could be a putative general agrochemical stress signal. My research indicates that gene expression profiles can be an excellent tool for discovering stressor-specific biomarkers and diagnosing stressors found in honey bee colonies.
dc.identifier.urihttp://hdl.handle.net/10315/41031
dc.languageen
dc.rightsAuthor owns copyright, except where explicitly noted. Please contact the author directly with licensing requests.
dc.subjectToxicology
dc.subjectEntomology
dc.subjectMolecular biology
dc.subject.keywordsRNA-Seq
dc.subject.keywordsTranscriptomics
dc.subject.keywordsDetoxification
dc.subject.keywordsBiomarkers
dc.subject.keywordsInsect
dc.subject.keywordsBee
dc.subject.keywordsPesticide
dc.subject.keywordsAgrochemical
dc.subject.keywordsMetabolism
dc.subject.keywordsToxicology
dc.subject.keywordsGenomics
dc.subject.keywordsToxicogenomics
dc.subject.keywordsDifferential expression analysis
dc.subject.keywordsApis mellifera
dc.subject.keywordsNurse
dc.subject.keywordsNeonicotinoid
dc.subject.keywordsOff-target
dc.subject.keywordsSystemic
dc.subject.keywordsDecline
dc.subject.keywordsMortality
dc.subject.keywordsmRNA
dc.subject.keywordsRNA
dc.subject.keywordsTranscripts
dc.subject.keywordsGene
dc.subject.keywordsAgriculture
dc.titleDevelopment of Exposure Biomarkers for the Honey Bee (Apis mellifera): Neonicotinoids Versus Traditional Pesticides
dc.typeElectronic Thesis or Dissertation

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