Outcomes and Cost of Women-Focused Cardiac Rehabilitation: A Systematic Review and Meta-analysis

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dc.contributor.authorMamataz, Taslima
dc.contributor.authorLima de Melo Ghisi, Gabriela
dc.contributor.authorPakosh, Maureen
dc.contributor.authorGrace, Sherry
dc.date.accessioned2023-02-10T22:56:18Z
dc.date.available2023-02-10T22:56:18Z
dc.date.issued2022-06
dc.description.abstractBackground: The aim of this systematic review was to investigate the effects of women-focused cardiac rehabilitation (CR) on patient outcomes and cost. Methods: Medline, Pubmed, Embase, PsycINFO, CINAHL, Web of Science, Scopus and Emcare were searched for articles from inception-May 2020. Primary studies of any design were included, with adult females with any cardiac diseases. “Women-focused” CR comprised programs or sessions with >50% females, or 1-1 programming tailored to women’s preferences. No studies were excluded based on outcome. Two independent reviewers rated citations for potential inclusion, and 1 extracted data, including quality, which was checked independently. Random-effects meta-analysis was used where there were ≥3 trials with the same outcome; Certainty of evidence for these was determined based on GRADE. For other outcomes, SWiM was applied. Results: 3498 unique citations were identified, of which 28 (52 papers) studies were included (3,697 participants; 11 trials). No meta-analysis could be performed for outcomes with usual care comparisons. When compared to active comparison, women-focused CR had no meaningful effect on functional capacity. Women-focused CR meaningfully improved physical (mean difference [MD]=6.37, 95% confidence interval [CI]=3.14-9.59; I2=0%; moderate-quality evidence), and mental (MD=4.66, 95% CI=0.21-9.11; I2=36%; low-quality evidence) quality of life, as well as 7/8 SF-36 domains. Qualitatively, results showed women-focused CR was associated with lower morbidity, risk factors, and greater psychosocial well-being. No effect was observed for mortality. One study reported favorable economic impact and another reduced sick days. Conclusions: Women-focused CR is associated with clinical benefit, although there is mixed evidence and more research is needed.en_US
dc.description.sponsorshipS.L.G. is supported in her work by the Toronto General & Toronto Western Hospital Foundation and the Peter Munk Cardiac Centre, University Health Networken_US
dc.identifier.citationMamataz, Ghisi, G. L., Pakosh, M., & Grace, S. L. (2022). Outcomes and cost of women-focused cardiac rehabilitation: A systematic review and meta-analysis. Maturitas, 160, 32–60. https://doi.org/10.1016/j.maturitas.2022.01.008en_US
dc.identifier.issn0378-5122
dc.identifier.urihttps://doi.org/10.1016/j.maturitas.2022.01.008en_US
dc.identifier.urihttp://hdl.handle.net/10315/40875
dc.language.isoenen_US
dc.publisherMaturitasen_US
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.articlehttps://doi.org/10.1016/j.maturitas.2022.01.008en_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectCardiac rehabilitationen_US
dc.subjectSystematic reviewen_US
dc.subjectMortalityen_US
dc.subjectHeart disease risk factorsen_US
dc.subjectQuality of lifeen_US
dc.titleOutcomes and Cost of Women-Focused Cardiac Rehabilitation: A Systematic Review and Meta-analysisen_US
dc.typeArticleen_US

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