Cadwallader, DustyTiburcio, Tristan R.Cieszynski, George A.Le, Christine M.2023-06-022023-06-022022-08-16J. Org. Chem. 2022, 87, 17, 11457–1146810.1021/acs.joc.2c01017http://hdl.handle.net/10315/41192We report a method for the synthesis of carbamoyl fluorides from secondary amines using bench-stable, inexpensive, and readily accessible starting materials that, when combined, yield a surrogate for toxic difluorophosgene (COF2) gas. In contrast to state-of-the-art methods for the synthesis of carbamoyl fluorides, our protocol does not require the use of pre-functionalized substrates, the preparation of light-, temperature-, and/or moisture-sensitive chemicals, or the application of explosive fluorinating reagents.enAttribution-NonCommercial-NoDerivatives 4.0 Internationaldifluorocarbene, carbamoyl fluorides, fluorinationArticle